My personal focus was on a crucial component of the app that is used by participants to self-report on the progress of the trial without needing to visit their physician. This was extremely due to brutal constraints: the reporting forms in their original paper form have been around often for 20-30 years and have been used to collect huge body of data over the years.

Therefore the starting point is "you cannot change anything", because every single change, no matter how tiny, may affect and bias the data collected. And biased data means failed trial, which ultimately means lives lost. Let alone the billions of dollars lost (average cost of a clinical trial is $2.6B and average duration is 12 years). The problem is you cannot just show a full paper form on a phone display, because that would be illegible and unusable. So by default, this is almost mission impossible. It might as well be the most sensitive and serious app design work in the world.

We spent a lot of time understanding every single piece of requirements on a scientific level. We regularly worked with science experts to assess various options what can be changed and how much, what would make most sense from user perspective and where is the middle ground between user requirements and science requirements. This is a diligent, sensitive and complex work and I could spend hours explaining the complexities of it.